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Translocation is the
rearrangement of parts between nonhomologous chromosomes.
·
No loss or gain of
genetic material is balanced translocation and with less or more of genetic
material is unbalanced translocation leading to abnormality.
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Two types of
translocations are reciprocal and Robertsonian translocation
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Reciprocal
translocation: it is formed when a break occurs in each of two chromosomes with
the segments being exchanged to form to form two new derivative chromosomes.
·
Robertsonian
translocation: it is a particular type of reciprocal translocation in which
breaking points are located at, or close to , centromeres of two acrocentric
chromosomes.
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